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Article

Circulating tumor DNA sequencing in colorectal cancer patients treated with first-line chemotherapy with anti-EGFR.

Scientific reports - 11 Aug 2021

Lim Yoojoo, Kim Sheehyun, Kang Jun-Kyu, Kim Hwang-Phill, Jang Hoon, Han Hyojun, Kim Hyoki, Kim Min Jung, Lee Kyung-Hun, Ryoo Seung-Bum, Park Ji Won, Jeong Seung-Yong, Park Kyu Joo, Kang Gyeong Hoon, Han Sae-Won, Kim Tae-You

Abstract excerpt

Circulating tumor DNA (ctDNA) may reveal dynamic tumor status during therapy. We conducted serial ctDNA analysis to investigate potential association with clinical outcome in metastatic colorectal cancer (mCRC) patients receiving chemotherapy. Tissue KRAS/NRAS wild-type mCRC patients were enrolled and treated with first-line cetuximab-containing chemotherapy. ctDNA isolated from plasma were analyzed by next...

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Share to Antineoplastic Agents, Immunological
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34381078
DOI: 10.1038/s41598-021-95345-4
PMCID: PMC8358023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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