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Article

Intratumoral heterogeneity of endogenous tumor cell invasive behavior in human glioblastoma

14 Dec 2018

Abstract excerpt

Intratumoral genetic heterogeneity is a widely accepted characteristic of human cancer, including the most common primary malignant brain tumor, glioblastoma. However, the variability in biological behaviors amongst cells within individual tumors is not well described. Invasion into unaffected brain parenchyma is one such behavior, and a leading mechanism of tumor recurrence unaddressed by the current therapeutic...

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PMID: 30573757
DOI: 10.1038/s41598-018-36280-9

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