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Mutational landscape of gastric cancer and clinical application of genomic profiling based on target next-generation sequencing

4 Jun 2019

Abstract excerpt

BACKGROUND: Gastric cancer (GC) is a leading cause of cancer deaths, and an increased number of GC patients adopt to next-generation sequencing (NGS) to identify tumor genomic alterations for precision medicine. METHODS: In this study, we established a hybridization capture-based NGS panel including 612 cancer-associated genes, and collected sequencing data of tumors and matched bloods from 153 gastric cancer...

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PMID: 31164161
DOI: 10.1186/s12967-019-1941-0

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