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CDKN2A Deletion Leading to Hematogenous Metastasis of Human Gastric Carcinoma

23 Dec 2021

Abstract excerpt

Introduction Somatic copy number deletion (SCND) of CDKN2A gene is the most frequent event in cancer genomes. Whether CDKN2A SCND drives human cancer metastasis is far from clear. Hematogenous metastasis is the main reason of human gastric carcinoma (GC) death. Thus, prediction GC metastasis is eagerly awaited. Method GC patients (n=408) enrolled in both a cross-sectional and a prospective cohorts were analysed....

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PMID: 35004325
DOI: 10.3389/fonc.2021.801219

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