Article
Mutational signatures in 175 Chinese gastric cancer patients.
BMC cancer - 30 Sept 2024
Liu Fatao, Hu Nan, Jiang Kewei, Liu Huaitian, Wang Mingyi, Hu Ying, Zhang Tongwu, Wu Ho-Hsiang, Yang Howard, Weng Hao, Dong Ping, Giffen Carol, Zhu Bin, Lee Maxwell P, Abnet Christian C, Taylor Philip R, Liu Yun, Liu Yingbin, Goldstein Alisa M
Abstract excerpt
BACKGROUND: Gastric cancer (GC), a molecularly heterogeneous disease, is the third leading cause of cancer death worldwide. The majority of GC cases worldwide occur in East Asia, predominantly China. Mutational Signature Framework offers an elegant approach to identify mutational processes present in tumors. METHODS: To identify mutational signature patterns, we conducted whole exome sequencing (WES) analysis in...
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