Article
Different patterns of gray matter atrophy in early- and late-onset Alzheimer's disease.
Neurobiology of aging - 1 Aug 2013
Möller Christiane, Vrenken Hugo, Jiskoot Lize, Versteeg Adriaan, Barkhof Frederik, Scheltens Philip, van der Flier Wiesje M
Abstract excerpt
We assessed patterns of gray matter atrophy according to-age-at-onset in a large sample of 215 Alzheimer's disease (AD) patients and 129 control subjects with voxel-based morphometry using 3-Tesla 3D T1-weighted magnetic resonance imaging. Local gray matter amounts were compared between late- and early-onset AD patients and older and younger control subjects, taking into account the effect of apolipoprotein E....
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