Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland

11 Dec 2018

Abstract excerpt

The organization of the extracellular matrix has a profound impact on cancer development and progression. The matrix becomes aligned throughout tumor progression, providing “highways” for tumor cell invasion. Aligned matrix is associated with breast density and is a negative prognostic factor in several cancers; however, the underlying mechanisms regulating this reorganization remain poorly understood. Deletion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30550871
DOI: 10.1016/j.neo.2018.10.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary GlandPMID 30550871Read ↗

Complex mechanics of the heterogeneous extracellular matrix in cancerSemantic proximity Read ↗

The Mechanics of Tumor Cells Dictate Malignancy via Cytoskeleton-Mediated APC/Wnt/β-Catenin SignalingSemantic proximity Read ↗

Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imagingSemantic proximity Read ↗

Tensional homeostasis and the malignant phenotype.Semantic proximity Read ↗

PTEN regulates fibroblast elimination during collagen matrix contraction.Semantic proximity Read ↗

Tumor extracellular matrix: lessons from the second-harmonic generation microscopySemantic proximity Read ↗

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.Semantic proximity Read ↗

PTEN controls junction lengthening and stability during cell rearrangement in epithelial tissue.Semantic proximity Read ↗

Modeling glands with PTEN deficient cells and microscopic methods for assessing PTEN loss: endometrial cancer as a model.Semantic proximity Read ↗

Force-exerting lateral protrusions in fibroblastic cell contractionSemantic proximity Read ↗

Disassembly of hemidesmosomes promotes tumorigenesis in PTEN-negative prostate cancer by targeting plectin into focal adhesionsSemantic proximity Read ↗

Mitotic spindle orientation in epithelial homeostasis and plasticitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.