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Article

Glycogen Synthase Kinase 3β Enhances Hepatitis C Virus Replication by Supporting miR-122

27 Nov 2018

Abstract excerpt

Hepatitis C virus (HCV) infection is associated with alterations in host lipid and insulin signaling cascades, which are partially explained by a dependence of the HCV life cycle on key molecules in these metabolic pathways. Yet, little is known on the role in the HCV life cycle of glycogen synthase kinase 3 (GSK3), one of the most important kinases in cellular metabolism. Therefore, the impact of GSK3 on the HCV...

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PMID: 30542341
DOI: 10.3389/fmicb.2018.02949

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