Article
Increased hepatic expression of miRNA-122 in patients infected with HCV genotype 3.
Medical microbiology and immunology - 1 Apr 2016
Oliveira Ketti G, Malta Fernanda M, Nastri Ana C S S, Widman Azzo, Faria Paola L, Santana Rúbia A F, Alves Venâncio A F, Carrilho Flair J, Pinho João R R
Abstract excerpt
Hepatitis C virus (HCV) infection affects approximately 3 % of the world population. HCV targets hepatic tissue, and most infected patients develop a chronic infection. Currently, studies have demonstrated an association between HCV-RNA replication and miR-122, the most abundant microRNA in the liver. Our aim was to evaluate liver and serum expression of miR-122 in patients infected with HCV genotypes 1 and 3,...
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