Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay

4 May 2017

Abstract excerpt

Reactivation of latent viral reservoirs is on the forefront of HIV-1 eradication research. However, it is unknown if latency reversing agents (LRAs) increase the level of viral transcription from cells producing HIV RNA or harboring transcriptionally-inactive (latent) infection. We therefore developed a microfluidic single-cell-in-droplet (scd)PCR assay to directly measure the number of CD4 + T cells that produce...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28529033
DOI: 10.1016/j.ebiom.2017.05.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR AssayPMID 28529033Read ↗

Adaptation of Droplet Digital PCR-Based HIV Transcription Profiling to Digital PCR and Association of HIV Transcription and Total or Intact HIV DNASemantic proximity Read ↗

Assessment of the HIV-1 reservoir in CD4+ regulatory T cells by a Droplet Digital PCR based approachSemantic proximity Read ↗

Diagnostic utility of droplet digital PCR for HIV reservoir quantificationSemantic proximity Read ↗

Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral LatencySemantic proximity Read ↗

Highly Precise Measurement of HIV DNA by Droplet Digital PCRSemantic proximity Read ↗

Quantification of HIV-DNA and residual viremia in patients starting ART by droplet digital PCR: Their dynamic decay and correlations with immunological parameters and virological successSemantic proximity Read ↗

Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latencySemantic proximity Read ↗

Accurate bulk quantitation of droplet digital PCRSemantic proximity Read ↗

Silencing the transcriptionally active HIV reservoir to improve treatment outcomesSemantic proximity Read ↗

Quantification of Total HIV DNA as a Marker to Measure Viral Reservoir: Methods and Potential Implications for Clinical PracticeSemantic proximity Read ↗

Comparison of Droplet Digital PCR and Seminested Real-Time PCR for Quantification of Cell-Associated HIV-1 RNASemantic proximity Read ↗

HIV-1 persistence during ARTSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.