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Article

Cutting edge: resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2006

Jennes Wim, Verheyden Sonja, Demanet Christian, Adjé-Touré Christiane A, Vuylsteke Bea, Nkengasong John N, Kestens Luc

Abstract excerpt

NK cells are regulated in part by killer Ig-like receptors (KIR) that interact with HLA molecules on potential target cells. KIR and HLA loci are highly polymorphic and certain KIR/HLA combinations were found to protect against HIV disease progression. We show in this study that KIR/HLA interactions also influence resistance to HIV transmission. HIV-exposed but seronegative female sex workers in Abidjan, Côte...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Immunologic

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Source

Identifiers

PMID: 17082569
DOI: 10.4049/jimmunol.177.10.6588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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