Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation

5 Dec 2018

Abstract excerpt

Background Nephron number is a major determinant of long-term renal function and cardiovascular risk. Observational studies suggest that maternal nutritional and metabolic factors during gestation contribute to the high variability of nephron endowment. However, the underlying molecular mechanisms have been unclear. Methods We used mouse models, including DNA methyltransferase ( Dnmt1, Dnmt3a, and Dnmt3b )...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Pregnancy and preeclampsia studies
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30518531
DOI: 10.1681/asn.2018070736

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and DifferentiationPMID 30518531Read ↗

Maternal malnutrition in mice impairs nephrogenesis by disrupting DNA methylation of regulatory regionsSemantic proximity Read ↗

Tet2- and Tet3-Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron EndowmentSemantic proximity Read ↗

Dnmt3a and Dnmt3b-Decommissioned Fetal Enhancers are Linked to Kidney DiseaseSemantic proximity Read ↗

The Impact of Low Protein Diet on the Molecular and Cellular Development of the Fetal KidneySemantic proximity Read ↗

Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem CellsSemantic proximity Read ↗

DNA methylation in chronic kidney diseaseSemantic proximity Read ↗

DNMT1 overexpression disrupts DNA methylation homeostasis in mouse embryonic stem cellsSemantic proximity Read ↗

Deletion of NuRD component <i>Mta2</i> in nephron progenitor cells causes developmentally programmed FSGSSemantic proximity Read ↗

Small non-coding RNA expression in developing mouse nephron progenitor cellsSemantic proximity Read ↗

Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development.Semantic proximity Read ↗

Are Alterations in DNA Methylation Related to CKD Development?Semantic proximity Read ↗

Forming nephrons promote nephron progenitor maintenance and branching morphogenesis via paracrine BMP4 signalling under the control of <i>Wnt4</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.