Article

Transglutaminase 2 predicts parasitic worm-mediated protection against hepatic steatosis in obese mice

2025-11-21

Abstract excerpt

Parasitic worm infection can mitigate high fat diet-induced chronic inflammation in obese mice by reducing hepatic fat accumulation and improving insulin sensitivity. However, the molecular alterations during infection-mediated regulation of hepatic steatotic events in obesity remain poorly understood. Here, we integrated proteomic and metabolomic analyses of infected obese mice, a functional deworming and interle...

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Literature Corpus work: 865c1926-bfaa-58bb-b019-41c2dda8812f
DOI: 10.1101/2025.11.21.689654

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