Article

Host-Pathogen Interactions in the <i>Plasmodium</i> -Infected Mouse Liver at Spatial and Single-Cell Resolution

2023-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Upon infecting its vertebrate host, the malaria parasite initially invades the liver where it undergoes massive replication, whilst remaining clinically silent. The spatial coordination of factors regulating immune responses and metabolic zonation during malaria infection, in the true tissue context, remains unexplored. Here, we perform spatial transcriptomics in combination with single-nuclei R...

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Literature Corpus work: c6c5183f-2e5a-5a49-9e4d-7ee6607d56bc
DOI: 10.1101/2023.12.22.573046

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