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Article

<i>Schistosoma mansoni</i> infection reprograms the metabolic potential of the myeloid lineage in a mouse model of metabolic syndrome

2020-04-20

Abstract excerpt

<h4>Summary</h4> Despite evidence that helminths protect from metabolic disease, a major gap exists in understanding the underlying mechanism(s). Here we demonstrate that bone marrow derived macrophages (BMDM) from S. mansoni infected male ApoE -/- mice have dramatically increased mitochondrial respiration compared to those from uninfected mice. This change associates with increased glucose and palmitate shuttl...

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Identifiers and source

Literature Corpus work
f2eeab04-3a04-5c15-a67e-ad29c0b099e9
DOI
10.1101/2020.04.20.050898
Open publication

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<i>Schistosoma mansoni</i> infection reprograms the metabolic potential of the myeloid lineage in a mouse model of metabolic syndromeDOI 10.1101/2020.04.20.050898
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