Article

GWAS Reveals Distinct Genetic Architecture of Schistosomiasis-Induced Hepatic Fibrosis with <i>DGKG</i> as a Key Mediator

2026-03-24

Abstract excerpt

<h4>Background & Aims</h4> Schistosomiasis is a major cause of hepatic fibrosis in endemic regions, yet the host genetic determinants of disease progression remain poorly defined. We aimed to identify genetic drivers and underlying mechanisms of schistosomiasis-induced hepatic fibrosis. <h4>Methods</h4> We performed a genome-wide association study (GWAS) of 984 Schistosoma japonicum -infected individuals from h...

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Literature Corpus work: ed91f5de-08f5-5177-bd8c-eaa7a5af1ee0
DOI: 10.64898/2026.03.21.26348960

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