Article
Metabolic regulation of macrophage phenotype and function.
Immunological reviews - 1 Nov 2017
Saha Shilpi, Shalova Irina N, Biswas Subhra K
Abstract excerpt
Studies in the last 20 years have given us a remarkable insight into the functional and phenotypic diversity of macrophages which reflects their integral role in host defence, homeostasis and pathogenesis. Mouse genetics, transcriptomic and epigenetic studies have provided an ontogenic and molecular perspective to the phenotypic diversity of these cells. Recently, metabolic studies have revealed the crucial role...
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