Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Independent associations of TOMM40 and APOE variants with body mass index

21 Nov 2018

Abstract excerpt

Abstract The TOMM40‐APOE variants are known for their strong, antagonistic associations with Alzheimer's disease and body weight. While a stronger role of the APOE than TOMM40 variants in Alzheimer's disease was suggested, comparative contribution of the TOMM40‐APOE variants in the regulation of body weight remains elusive. We examined additive effects of rs2075650 and rs157580 TOMM40 variants and rs429358 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet and metabolism studies
Share to Genetic Associations and Epidemiology
Share to Genetics, Aging, and Longevity in Model Organisms

Source

Identifiers

PMID: 30462377
DOI: 10.1111/acel.12869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Independent associations of TOMM40 and APOE variants with body mass indexPMID 30462377Read ↗

Extension of Mendelian Randomization to Identify Earliest Manifestations of Alzheimer Disease: Association of Genetic Risk Score for Alzheimer Disease With Lower Body Mass Index by Age 50 Years.Semantic proximity Read ↗

Mediation of the APOE associations with Alzheimer's and coronary heart diseases through body mass index and lipids.Semantic proximity Read ↗

The Synergistic Effects of APOE Genotype and Obesity on Alzheimer’s Disease RiskSemantic proximity Read ↗

Unravelling the Relationship Between Height, Lean Mass, Alzheimer’s Disease and Cognition Through Mendelian RandomizationSemantic proximity Read ↗

Association of genetic risk score for Alzheimer's disease with late-life body mass index in all of us: Evaluating reverse causation.Semantic proximity Read ↗

Obesity-related brain atrophy is independent of Alzheimer’s disease protein pathwaysSemantic proximity Read ↗

Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk.Semantic proximity Read ↗

Protective association of the ε2/ε3 heterozygote with Alzheimer's disease is strengthened by TOMM40-APOE variants in men.Semantic proximity Read ↗

Alzheimer’s Disease: Causal Effect between Obesity and APOE Gene PolymorphismsSemantic proximity Read ↗

The apolipoprotein E polymorphism rs7412 associates with body fatness independently of plasma lipids in middle aged men.Semantic proximity Read ↗

The Obesity Related Gene, FTO, Interacts with APOE, and is Associated with Alzheimer's Disease Risk: A Prospective Cohort StudySemantic proximity Read ↗

Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.