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Article

Antibacterial agents specifically inhibiting lipopolysaccharide synthesis.

Nature - 1 Jan 2000

Goldman R, Kohlbrenner W, Lartey P, Pernet A

Abstract excerpt

The spread of antibiotic resistance in Gram-negative bacteria has sustained a continuing search for new agents with antibacterial activity against this important class of bacterial pathogen. Because the biosynthesis of lipopolysaccharide (LPS) is unique to Gram-negative bacteria and required by t...

Topics

Aldehyde-Lyases
Amino Sugars
Aminopeptidases
Anti-Bacterial Agents
Drug Resistance, Microbial
Genes
Genes, Bacterial
Genotype
Kinetics
Lipopolysaccharides
Mutation
Nucleotidyltransferases
Salmonella typhimurium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sugar Acids

Source

Identifiers

PMID: 3041230
DOI: 10.1038/329162a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3041230-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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