Article
Cellular senescence at the crossroads of inflammation and Alzheimer's disease.
Trends in neurosciences - 1 Sept 2021
Guerrero Ana, De Strooper Bart, Arancibia-Cárcamo I Lorena
Abstract excerpt
Aging is a key risk factor for Alzheimer's disease (AD), but the reasons for this association are not well understood. Senescent cells accumulate in aged tissues and have been shown to play causal roles in age-related pathologies through their proinflammatory secretome. The question arises whether senescence-induced inflammation might contribute to AD and bridge the gap between aging and AD. Here, we highlight...
Topics
Join the communities discussing this publication.