Article
Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial
19 Oct 2018
Abstract excerpt
BACKGROUND: Cytokines are critical to human disease and are attractive therapeutic targets given their widespread influence on gene regulation and transcription. Defining the downstream regulatory mechanisms influenced by cytokines is central to defining drug and disease mechanisms. One promising strategy is to use interactions between expression quantitative trait loci (eQTLs) and cytokine levels to define...
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