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Article

Defective autophagy in vascular smooth muscle cells enhances atherosclerotic plaque instability

11 Oct 2018

Abstract excerpt

Autophagy is considered as an evolutionarily conserved cellular catabolic process. Defective autophagy has been implicated in various human diseases, including cardiovascular diseases. Recently, we and others demonstrated that defective autophagy in vascular smooth muscle cells (SMCs) promotes the progression of atherosclerosis. In this study, we investigated the role of autophagy in SMCs on plaque instability in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30318118
DOI: 10.1016/j.bbrc.2018.09.192

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