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Article

Defective Autophagy in Atherosclerosis: To Die or to Senesce?

1 Jan 2018

Abstract excerpt

Autophagy is a subcellular process that plays an important role in the degradation of proteins and damaged organelles such as mitochondria (a process termed "mitophagy") via lysosomes. It is crucial for regulating protein and mitochondrial quality control and maintaining cellular homeostasis, whereas dysregulation of autophagy has been implicated in a wide range of diseases including atherosclerosis. Recent...

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PMID: 29682164
DOI: 10.1155/2018/7687083

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