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Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent.

Cell death and differentiation - 1 Jan 2024

Levine Arnold J, Carpten John D, Murphy Maureen, Hainaut Pierre

Abstract excerpt

Multiple Myeloma is a typical example of a neoplasm that shows significant differences in incidence, age of onset, type, and frequency of genetic alterations between patients of African and European ancestry. This perspective explores the hypothesis that both genetic polymorphisms and spontaneous somatic mutations in the TP53 tumor suppressor gene are determinants of these differences. In the US, the rates of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38001255
DOI: 10.1038/s41418-023-01236-8
PMCID: PMC10781774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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