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Article

DNA Damage Repair Deficiency in Prostate Cancer.

Trends in cancer - 1 Nov 2020

Burdak-Rothkamm Susanne, Mansour Wael Y, Rothkamm Kai

Abstract excerpt

Molecular-targeted therapies and treatment stratification based on molecular biomarkers have rapidly gained momentum in the therapeutic spectrum for patients with prostate cancer, particularly those with aggressive disease. DNA damage repair (DDR) pathways are commonly impaired in prostate cancer. Recent studies have detailed mechanisms interconnecting the DDR with the androgen receptor (AR) signaling pathway as...

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PMID: 32517958
DOI: 10.1016/j.trecan.2020.05.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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