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Article

Treatment strategies for DNA repair-deficient prostate cancer.

Expert review of clinical pharmacology - 1 Aug 2017

Teply Benjamin A, Antonarakis Emmanuel S

Abstract excerpt

INTRODUCTION: Common recurrent genetic alterations have been identified in prostate cancer through comprehensive sequencing efforts, and the prevalence of mutations in DNA repair pathway genes in patients with advanced and metastatic disease approaches 20-25%. Identification of these underlying DNA repair defects may present unique treatment opportunities for patients, both in terms of standard-of-care treatments...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28573914
DOI: 10.1080/17512433.2017.1338138
PMCID: PMC6088808

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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