Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Mechanisms of Prostate Cancer Development in the Precision Medicine Era: A Comprehensive Review

25 Jan 2024

Abstract excerpt

The progression of prostate cancer (PCa) relies on the activation of the androgen receptor (AR) by androgens. Despite efforts to block this pathway through androgen deprivation therapy, resistance can occur through several mechanisms, including the abnormal activation of AR, resulting in castration-resistant PCa following the introduction of treatment. Mutations, amplifications, and splicing variants in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Prostate Cancer Treatment and Research
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38339274
DOI: 10.3390/cancers16030523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Mechanisms of Prostate Cancer Development in the Precision Medicine Era: A Comprehensive ReviewPMID 38339274Read ↗

Molecular pathogenesis and progression of prostate cancer.Semantic proximity Read ↗

Recent advances in prostate cancer research: large-scale genomic analyses reveal novel driver mutations and DNA repair defectsSemantic proximity Read ↗

The Genetic Complexity of Prostate Cancer.Semantic proximity Read ↗

The molecular biology of prostate cancer: current understanding and clinical implications.Semantic proximity Read ↗

Precision Targets for Intercepting the Lethal Progression of Prostate Cancer: Potential Avenues for Personalized TherapySemantic proximity Read ↗

The molecular underpinnings of prostate cancer: impacts on management and pathology practiceSemantic proximity Read ↗

The genomic landscape of prostate cancerSemantic proximity Read ↗

The Genomic and Molecular Pathology of Prostate Cancer: Clinical Implications for Diagnosis, Prognosis, and TherapySemantic proximity Read ↗

Molecular landscape of prostate cancer: Implications for current clinical trialsSemantic proximity Read ↗

Molecular mechanisms and genetic alterations in prostate cancer: From diagnosis to targeted therapy.Semantic proximity Read ↗

Emerging Biomarker-Guided Therapies in Prostate CancerSemantic proximity Read ↗

Interactions between key genes and pathways in prostate cancer progression and therapy resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.