Article
Genetic association and differential expression of HLAComplexGroup lncRNAs in pemphigus.
Journal of autoimmunity - 1 Sept 2021
Salviano-Silva Amanda, Becker Mareike, Augusto Danillo G, Busch Hauke, Adelman Cipolla Gabriel, Farias Ticiana D-J, Bumiller-Bini Valéria, Calonga-Solís Verónica, Munz Matthias, Franke Andre, Wittig Michael, Camargo Carolina M, Goebeler Matthias, Hundt Jennifer Elisabeth, Günther Claudia, Gläser Regine, Hadaschik Eva, Pföhler Claudia, Sárdy Miklós, Van Beek Nina, Worm Margitta, Zillikens Detlef, Boldt Angelica B W, Schmidt Enno, Petzl-Erler Maria Luiza, Ibrahim Saleh, Malheiros Danielle
Abstract excerpt
BACKGROUND: Pemphigus is a group of bullous diseases characterized by acantholysis and skin blisters. As for other autoimmune diseases, the strongest genetic associations found so far for pemphigus foliaceus (PF) and vulgaris (PV) are with alleles of HLA genes. However, apart from protein-coding genes, the MHC region includes a set of poorly explored long non-coding RNA (lncRNA) genes, the HLA complex group...
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