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Article

A 3'UTR polymorphism marks differential KLRG1 mRNA levels through disruption of a miR-584-5p binding site and associates with pemphigus foliaceus susceptibility.

Biochimica et biophysica acta - 1 Oct 2016

Cipolla Gabriel A, Park Jong Kook, de Oliveira Liana A, Lobo-Alves Sara Cristina, de Almeida Rodrigo C, Farias Ticiana D J, Lemos Débora de S, Malheiros Danielle, Lavker Robert M, Petzl-Erler Maria Luiza

Abstract excerpt

Genetic variations mapping to 3' untranslated regions (3'UTRs) may overlap with microRNA (miRNA) binding sites, therefore potentially interfering with translation inhibition or messenger RNA (mRNA) degradation. The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) located within the 3'UTRs of six candidate genes and predicted to interfere with miRNA ligation could account for...

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Topics

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Share to 3' Untranslated Regions
Share to Antigens, CD1d

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to B-Cell Activating Factor

Share to CTLA-4 Antigen

Share to Lectins, C-Type

Share to Pemphigus

Share to Receptors, Immunologic

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Source

Open in PubMed Open full text

Identifiers

PMID: 27424220
DOI: 10.1016/j.bbagrm.2016.07.006
PMCID: PMC4997811

Genes

KLRG1
CTLA4
KLRD1
NKG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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