Article
Chromosome 2q33genetic polymorphisms in Tunisian endemic pemphigus foliaceus.
Molecular genetics & genomic medicine - 1 Nov 2020
Abida Olfa, Bahloul Emna, Ben Jmaa Mariem, Sellami Khadija, Zouidi Ferjani, Fakhfakh Raouia, Mahfoudh Nadia, Turki Hamida, Masmoudi Hatem
Abstract excerpt
BACKGROUND: Several studies have suggested that polymorphisms within genes encoding T-lymphocyte immune regulating molecules: CD28, CTLA-4, and ICOS, may alter the signaling process and subsequently could be involved in susceptibility to a broad spectrum of autoimmune diseases. METHODS: This study aimed to replicate associations between common polymorphisms in the 2q33.2 cluster and susceptibility to pemphigus...
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