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Article

A Novel Variant of Desmoplakin Is Potentially Associated with Silicosis Risk.

DNA and cell biology - 1 Nov 2018

Wang Wei, Yu Yuhui, Xiao Jing, Gao Yuexia, Sang Lingli, Lian Yulong, Lu Yihua, Tian Tian, Zhuang Xun, Han Lei, Chu Minjie

Abstract excerpt

Two genome-wide association studies and one sequencing study have coincidently reported significant associations of single nucleotide polymorphisms (SNPs) in the desmoplakin (DSP) gene with the risk of pulmonary fibrosis (mainly idiopathic pulmonary fibrosis). However, these findings have not been well generalized to occupational pulmonary fibrosis (e.g., silica-related silicosis). We systematically genotyped 8...

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Identifiers

PMID: 30207747
DOI: 10.1089/dna.2018.4370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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