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Article

The single nucleotide polymorphism rs1814521 in long non-coding RNA ADGRG3 associates with the susceptibility to silicosis: a multi-stage study.

Environmental health and preventive medicine - 1 Jan 2022

Wang Wei, Chen Xiaofeng, Li Chunping, Zhao Rui, Zhang Jinlong, Qin Hong, Wang Miaomiao, Su Yao, Tang Minzhu, Han Lei, Sun Na

Abstract excerpt

BACKGROUND: This study aimed to evaluate the correlation between long non-coding RNA (lncRNA)-related single nucleotide polymorphisms (SNPs) and susceptibility to silicosis. METHODS: First, RNA-sequencing (RNA-seq) data were comprehensively analyzed in the peripheral blood lymphocytes of eight participants (four silicosis cases and four healthy controls) exposed to silica dust to identify differentially expressed...

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Identifiers

PMID: 35289324
DOI: 10.1265/ehpm.21-00338
PMCID: PMC9093617

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