Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Desmoplakin Variants Are Associated with Idiopathic Pulmonary Fibrosis.

American journal of respiratory and critical care medicine - 15 May 2016

Mathai Susan K, Pedersen Brent S, Smith Keith, Russell Pamela, Schwarz Marvin I, Brown Kevin K, Steele Mark P, Loyd James E, Crapo James D, Silverman Edwin K, Nickerson Deborah, Fingerlin Tasha E, Yang Ivana V, Schwartz David A

Abstract excerpt

RATIONALE: Sequence variation, methylation differences, and transcriptional changes in desmoplakin (DSP) have been observed in patients with idiopathic pulmonary fibrosis (IPF). OBJECTIVES: To identify novel variants in DSP associated with IPF and to characterize the relationship of these IPF sequence variants with DSP gene expression in human lung. METHODS: A chromosome 6 locus (7,370,061-7,606,946) was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Desmoplakins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DSP gene

Share to Gene Expression

Share to Genetic Variation

Share to Idiopathic Pulmonary Fibrosis

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Share to Odds Ratio

Source

Open in PubMed Open full text

Identifiers

PMID: 26669357
DOI: 10.1164/rccm.201509-1863OC
PMCID: PMC4872666

Genes

DSP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Desmoplakin Variants Are Associated with Idiopathic Pulmonary Fibrosis.PMID 26669357Read ↗

Genome-Wide Association Study: Functional Variant rs2076295 Regulates Desmoplakin Expression in Airway Epithelial Cells.Semantic proximity Read ↗

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.Semantic proximity Read ↗

Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis.Semantic proximity Read ↗

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis.Semantic proximity Read ↗

A Novel Variant of Desmoplakin Is Potentially Associated with Silicosis Risk.Semantic proximity Read ↗

Targeted resequencing reveals genetic risks in patients with sporadic idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Identification of a novel missense variant in <i>SPDL1</i> associated with idiopathic pulmonary fibrosisSemantic proximity Read ↗

DSP rs2076295 variants influence nintedanib and pirfenidone outcomes in idiopathic pulmonary fibrosis: a pilot study.Semantic proximity Read ↗

Common single nucleotide polymorphisms associated with idiopathic pulmonary fibrosis: a systematic review.Semantic proximity Read ↗

Reversing Mechanoinductive DSP Expression by CRISPR/dCas9–mediated Epigenome EditingSemantic proximity Read ↗

Altered DNA Methylation Profile in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.