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Article

GNAS, GNAQ, and GNA11 alterations in patients with diverse cancers.

Cancer - 15 Oct 2018

Parish Austin J, Nguyen Vi, Goodman Aaron M, Murugesan Karthikeyan, Frampton Garrett M, Kurzrock Razelle

Abstract excerpt

BACKGROUND: Advances in deep sequencing technology have uncovered a widespread, protumorigenic role of guanine nucleotide-binding (G protein) α (GNA) subunits, particularly GNA subunits Gs (GNAS), Gq (GNAQ), and G11 (GNA11) (GNA*), in a diverse collection of malignancies. The objectives of the current study were: 1) to determine GNA* aberration status in a cohort of 1348 patients with cancer and 2) to examine...

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Identifiers

PMID: 30204251
DOI: 10.1002/cncr.31724
PMCID: PMC6234097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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