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Article

Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years.

Nature communications - 10 Sept 2018

Hofvander Jakob, Viklund Björn, Isaksson Anders, Brosjö Otte, Vult von Steyern Fredrik, Rissler Pehr, Mandahl Nils, Mertens Fredrik

Abstract excerpt

To compare clonal evolution in tumors arising through different mechanisms, we selected three types of sarcoma-amplicon-driven well-differentiated liposarcoma (WDLS), gene fusion-driven myxoid liposarcoma (MLS), and sarcomas with complex genomes (CXS)-and assessed the dynamics of chromosome and nucleotide level mutations by cytogenetics, SNP array analysis and whole-exome sequencing. Here we show that the...

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Identifiers

PMID: 30201954
DOI: 10.1038/s41467-018-06098-0
PMCID: PMC6131146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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