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Article

Describing the Mutational Characteristics of Myxofibrosarcoma: An AACR Project GENIE Analysis.

Anticancer research - 1 Feb 2026

Nooney Marlaena, Rigden Bryce, Torbenson Elijah, Braaten Marco, Hsia Beau, Mathews Abraham, Tauseef Abubakar

Abstract excerpt

BACKGROUND/AIM: Myxofibrosarcomas (MFS) are highly infiltrative soft tissue sarcomas that most commonly occur in adults within the sixth to seventh decades. Diagnosis relies on histopathological analysis as no definitive molecular markers have been identified. This study seeks to describe the mutational landscape of MFS, characterize mutations unique to certain populations, and identify mutations that may be of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41617429
DOI: 10.21873/anticanres.17990

Genes

RB1
ALOX12B
NCOA2
NF1
SDHA
TP53
ATRX
CDKN2A
CDKN2B
ETV6
FLCN
MAP2K4
NCOR1
NOTCH3
SOS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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