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Article

Comparative performance of warfarin pharmacogenetic algorithms in Chinese patients.

Thrombosis research - 1 Sept 2012

Liu Yu, Yang Jie, Xu Qiang, Xu Bin, Gao Lei, Zhang Yuxiao, Zhang Yan, Wang Hongjuan, Lu Caiyi, Zhao Yusheng, Yin Tong

Abstract excerpt

INTRODUCTION: Multiple warfarin pharmacogenetic algorithms have been confirmed to predict warfarin dose more accurately than clinical algorithm or the fixed-dose approach. However, their performance has never been objectively evaluated in patients under low intensity warfarin anticoagulation, which is optimal for prevention of thromboembolism in Asian patients. MATERIAL AND METHODS: We sought to compare the...

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PMID: 22374335
DOI: 10.1016/j.thromres.2012.02.003

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VKORC1

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