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Article

Primary biliary cholangitis: A tale of epigenetically-induced secretory failure?

Journal of hepatology - 1 Dec 2018

Rodrigues Pedro M, Perugorria Maria J, Santos-Laso Alvaro, Bujanda Luis, Beuers Ulrich, Banales Jesus M

Abstract excerpt

Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease associated with autoimmune-related destruction of small to medium size intrahepatic bile ducts. The aetiology of PBC is unknown and its pathogenesis remains obscure. Both genetic variants and environmental factors have been linked to increased PBC susceptibility, with other alterations known to cooperate in disease pathobiology. Increasing...

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Share to Autoantibodies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Liver Cirrhosis, Biliary

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Source

Identifiers

PMID: 30193962
DOI: 10.1016/j.jhep.2018.08.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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