Article
Epigenetics of Primary Biliary Cholangitis.
Advances in experimental medicine and biology - 1 Jan 2020
Li Yikang, Tang Ruqi, Ma Xiong
Abstract excerpt
Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease with non-suppurative destruction of the intrahepatic bile ducts. The interplay of genetics and environmental triggers contributes to the onset of the disease and subsequently results in cholestasis and progressive fibrosis. Recently, genome-wide association studies (GWAS) have identified multiple genes influencing the susceptibility to PBC...
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