Article
The prevalence of antibodies against the HLA-DRB3 protein in kidney transplantation and the correlation with HLA expression.
PloS one - 1 Jan 2018
Habets Thomas H P M, Hepkema Bouke G, Kouprie Niels, Schnijderberg Melanie C A, van Smaalen Tim C, Bungener Laura B, Christiaans Maarten H L, Bos Gerard M J, Vanderlocht Joris
Abstract excerpt
Human leukocyte antigen (HLA)-DRB3 is a functional HLA class II gene, which has a limited allele diversity in the human population. Furthermore, the HLA-DRB3 gene is only present in a subset of individuals. Therefore, in organ transplantation, this HLA molecule is frequently mismatched between patient and graft donor and thus antibodies against this mismatched HLA molecule can develop. In this study, we aimed to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.