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HLA-DQ antibodies in alloimmunity, what makes them different?

23 May 2023

Abstract excerpt

PURPOSE OF REVIEW: De novo HLA-DQ antibodies are the most frequently observed after solid-organ allotransplantation; and are associated with the worse adverse graft outcomes compared with all other HLA antibodies. However, the biological explanation for this observation is not yet known. Herein, we examine unique characteristics of alloimmunity directed specifically against HLA-DQ molecules. RECENT FINDINGS:...

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PMID: 37219535
DOI: 10.1097/mot.0000000000001079

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