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Article

Homozygosity in any HLA locus is a risk factor for specific antibody production: the taboo concept 2.0.

Frontiers in immunology - 1 Jan 2024

Loeffler-Wirth Henry, Lehmann Claudia, Lachmann Nils, Doxiadis Ilias

Abstract excerpt

Objective: In a cooperative study of the University Hospital Leipzig, University of Leipzig, and the Charité Berlin on kidney transplant patients, we analysed the occurrence of HLA-specific antibodies with respect to the HLA setup of the patients. We aimed at the definition of specific HLA antigens towards which the patients produced these antibodies. Methods: Patients were typed for the relevant HLA determinants...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38840925
DOI: 10.3389/fimmu.2024.1384823
PMCID: PMC11150536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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