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Article

The association between ST18 gene polymorphism and severe pemphigus disease among Iranian population.

Experimental dermatology - 1 Dec 2018

Etesami Ifa, Seirafi Hassan, Ghandi Narges, Salmani Hamzeh, Arabpour Maedeh, Nasrollahzadeh Ali, Teimourpour Amir, Daneshpazhooh Maryam, Keramatipour Mohammad

Abstract excerpt

Recently, ST18 polymorphism has played a role in increasing the risk of pemphigus among some populations such as Egyptian and Jewish. In addition, a variant within the ST18 promoter gene was shown to induce ST18 upregulation and cytokine secretion leading to keratinocyte susceptibility to anti-desmoglein antibodies. Thus, the present study aimed to assess the ST18 single nucleotide polymorphisms (SNP)...

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Identifiers

PMID: 30192416
DOI: 10.1111/exd.13778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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