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Article

Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene.

PLoS genetics - 1 May 2016

Vodo Dan, Sarig Ofer, Geller Shamir, Ben-Asher Edna, Olender Tsviya, Bochner Ron, Goldberg Ilan, Nosgorodsky Judith, Alkelai Anna, Tatarskyy Pavel, Peled Alon, Baum Sharon, Barzilai Aviv, Ibrahim Saleh M, Zillikens Detlef, Lancet Doron, Sprecher Eli

Abstract excerpt

Pemphigus vulgaris (PV) is a life-threatening autoimmune mucocutaneous blistering disease caused by disruption of intercellular adhesion due to auto-antibodies directed against epithelial components. Treatment is limited to immunosuppressive agents, which are associated with serious adverse effects. The propensity to develop the disease is in part genetically determined. We therefore reasoned that the delineation...

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Identifiers

PMID: 27148741
DOI: 10.1371/journal.pgen.1006008
PMCID: PMC4858139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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