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Pemphigus: trigger and predisposing factors

27 Dec 2023

Abstract excerpt

Pemphigus is a life-threatening autoimmune blistering disease affecting skin and mucous membranes. Despite its etiopathogenesis remains largely unknown, several trigger and predisposing factors have been reported. Pemphigus is caused by autoantibodies that target desmoglein 1 and desmoglein 3, impacting desmosome function. However, circulating autoantibodies are often the consequence of a precipitating factor...

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PMID: 38213911
DOI: 10.3389/fmed.2023.1326359

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