Article
Signaling by discoidin domain receptor 1 in cancer metastasis.
Cell adhesion & migration - 1 Jan 2018
Gadiya Mayur, Chakraborty Goutam
Abstract excerpt
Collagen is the most abundant component of tumor extracellular matrix (ECM). ECM collagens are known to directly interact with the tumor cells via cell surface receptor and play crucial role in tumor cell survival and promote tumor progression. Collagen receptor DDR1 is a member of receptor tyrosine kinase (RTK) family with a unique motif in the extracellular domain resembling Dictyostelium discoideum protein...
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