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Article

A putative role for Discoidin Domain Receptor 1 in cancer chemoresistance.

Cell adhesion & migration - 1 Jan 2018

Ambrogio Chiara, Darbo Elodie, Lee Sam W, Santamaría David

Abstract excerpt

The Discoidin Domain Receptor 1 (DDR1) receptor tyrosine kinase performs pleiotropic functions in the control of cell adhesion, proliferation, survival, migration, and invasion. Aberrant DDR1 function as a consequence of either mutations or increased expression has been associated with various human diseases including cancer. Pharmacological inhibition of DDR1 results in significant therapeutic benefit in several...

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Identifiers

PMID: 29505315
DOI: 10.1080/19336918.2018.1445954
PMCID: PMC6363036

Genes

DDR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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