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Article

Discoidin domain receptors: A promising target in melanoma

4 Jul 2019

Abstract excerpt

The discoidin domain receptor 1 (DDR1) is a member of the receptor tyrosine kinase family that signals in response to collagen and that has been implicated in cancer progression. In the present study, we investigated the expression and role of DDR1 in human melanoma progression. Immunohistochemical staining of human melanoma specimens (n = 52) shows high DDR1 expression in melanoma lesions that correlates with...

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PMID: 31271515
DOI: 10.1111/pcmr.12809

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