Article
Discoidin domain receptor tyrosine kinases: new players in cancer progression.
Cancer metastasis reviews - 1 Jun 2012
Valiathan Rajeshwari R, Marco Marta, Leitinger Birgit, Kleer Celina G, Fridman Rafael
Abstract excerpt
Almost all human cancers display dysregulated expression and/or function of one or more receptor tyrosine kinases (RTKs). The strong causative association between altered RTK function and cancer progression has been translated into novel therapeutic strategies that target these cell surface receptors in cancer. Yet, the full spectrum of RTKs that may alter the oncogenic process is not completely understood....
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