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Article

Improved outcomes in PI3K-pathway-altered metastatic HPV oropharyngeal cancer.

JCI insight - 6 Sept 2018

Hanna Glenn J, Kacew Alec, Chau Nicole G, Shivdasani Priyanka, Lorch Jochen H, Uppaluri Ravindra, Haddad Robert I, MacConaill Laura E

Abstract excerpt

While it has been recognized that human papillomavirus-associated (HPV-associated) oropharyngeal cancer (OPC) portends an improved prognosis, distinct patterns of disease recurrence have emerged. Molecular characterization of this subset of HPV patients remains unexplored. We evaluated 52 metastatic HPV+ OPC patients from our institution and paired massively parallel sequencing data with clinical parameters and...

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Source

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Identifiers

PMID: 30185662
DOI: 10.1172/jci.insight.122799
PMCID: PMC6171803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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